{"title":"Protein C-Ets","description":"\u003ch2 class=\"highlited\" data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eAbout ETS2 \/ Protein C-ETS:\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp data-mce-fragment=\"1\"\u003eProtein C-ETS2 is a protein in humans that is encoded by the ETS2 gene. The protein encoded by this gene belongs to the ETS family of transcription factors.\u003cbr data-mce-fragment=\"1\"\u003eThe ETS2 gene encodes a transcription factor that regulates genes involved in development and apoptosis. The encoded protein is also a protooncogene and shown to be involved in the regulation of telomerase. A pseudogene of this gene is located on the X chromosome.\u003cbr data-mce-fragment=\"1\"\u003eETS2 is implicated in:\u003cbr data-mce-fragment=\"1\"\u003e●DNA binding\u003cbr data-mce-fragment=\"1\"\u003e●glucocorticoid receptor binding\u003cbr data-mce-fragment=\"1\"\u003e●nucleus\u003cbr data-mce-fragment=\"1\"\u003e●positive regulation of transcription from RNA polymerase II promoter\u003cbr data-mce-fragment=\"1\"\u003e●positive regulation of transcription, DNA-dependent\u003cbr data-mce-fragment=\"1\"\u003e●protein binding\u003cbr data-mce-fragment=\"1\"\u003e●RNA polymerase II regulatory region sequence-specific DNA binding\u003cbr data-mce-fragment=\"1\"\u003e●sequence-specific DNA binding transcription factor activity\u003cbr data-mce-fragment=\"1\"\u003e●skeletal system development\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eETS2 Interactions\u003c\/strong\u003e\u003cbr data-mce-fragment=\"1\"\u003eETS2 has been shown to interact with the following:\u003cbr data-mce-fragment=\"1\"\u003e●C-jun, a protein encoded by the JUN gene\u003cbr data-mce-fragment=\"1\"\u003e●Cyclin-dependent kinase 10, an enzyme in humans encoded by the CDK10 gene\u003cbr data-mce-fragment=\"1\"\u003e●ERG (ETS-related gene), an oncogene that is a member of the ETS (erythroblast transformation-specific) family of transcription factors\u003cbr data-mce-fragment=\"1\"\u003e●Myb, genes that are a part of a large gene family of transcription factors found in both animals and plants\u003cbr data-mce-fragment=\"1\"\u003e●ZMYND11 (Zinc finger MYND domain-containing protein 11), a protein in humans encoded by the ZMYND11 gene\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eProtein C-ETS Functions\u003c\/strong\u003e\u003cbr data-mce-fragment=\"1\"\u003eTranscription factor activating transcription. Binds specifically the DNA GGAA\/T core motif (Ets-binding site or EBS) in gene promoters and stimulates transcription.\u003cbr data-mce-fragment=\"1\"\u003eIts molecular functions include DNA binding, sequence-specific DNA binding, RNA polymerase II transcription regulatory region sequence-specific DNA binding, and glucocorticoid receptor binding.\u003c\/p\u003e","products":[{"product_id":"ets2-human","title":"ETS2 Human","description":"\u003cp\u003eV-Ets Avian Erythroblastosis Virus E26 Oncogene 2 Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eProtein C-ets-2, ETS2, V-Ets Avian Erythroblastosis Virus E26 Oncogene 2, V-ets erythroblastosis virus E26 oncogene homolog 2, ETS2IT1.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"5µg","offer_id":43174480379988,"sku":"PRO-2007","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20µg","offer_id":43174480412756,"sku":"PRO-2007","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":43174480445524,"sku":"PRO-2007","price":2700.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-ets2-human-PRO-2007.png?v=1776693448"}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/collections\/Image_f0d11659-b543-4578-bc36-056edfef11e4.png?v=1700646694","url":"https:\/\/prospecbio.com\/collections\/protein-c-ets.oembed","provider":"prospecbio","version":"1.0","type":"link"}