{"title":"NHP2","description":"\u003ch2 class=\"highlited\" data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eAbout NHP2:\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp data-mce-fragment=\"1\"\u003eThe function of NHP2 (NHP2 ribonucleoprotein) is to be a non-catalytic component of the H\/ACA small nucleolar ribonucleoprotein. It is essential for ribosome biogenesis and catalyses pseudouridylation of rRNA. Part of this is the isomerization of uridine.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eNHP2 Gene\u003c\/strong\u003e\u003cbr data-mce-fragment=\"1\"\u003eNHP2 is a gene that codes for protein. Dyskeratosis congenita, autosomal recessive 2, and autosomal recessive 1 are diseases linked to NHP2. Telomere C-strand (lagging strand) synthesis and ribosome biogenesis are two related processes in eukaryotes. Annotations in the gene ontology (GO) for this gene include snoRNA binding. RPL7A is a significant paralog of this gene.\u003cbr data-mce-fragment=\"1\"\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eNHP2 Function\u003c\/strong\u003e\u003cbr data-mce-fragment=\"1\"\u003eNHP2 is essential for ribosome synthesis and the preservation of telomeres. It is a component of the H\/ACA small nucleolar ribonucleoprotein (H\/ACA snoRNP) complex that catalyzes rRNA pseudouridylation. This entails isomerizing uridine such that the ribose is linked to C5 rather than the usual N1. Each rRNA can have up to 100 pseudouridine ('psi') residues, which may help to maintain the rRNA's shape. TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme, may also need proper processing or intranuclear trafficking.\u003cbr data-mce-fragment=\"1\"\u003eH\/ACA ribonucleoprotein complex subunit 2 is a protein that is encoded by the NHP2 gene in humans. The H\/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family includes this gene. SnoRNPs are engaged in several areas of rRNA processing and modification and are divided into two families: C\/D and H\/ACA.\u003c\/p\u003e","products":[{"product_id":"nhp2-human","title":"NHP2 Human","description":"\u003cp\u003eNHP2 Ribonucleoprotein Homolog Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eH\/ACA ribonucleoprotein complex subunit 2, Nucleolar protein family A member 2, snoRNP protein NHP2, NHP2, NOLA2, NHP2P.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"5µg","offer_id":43174257754196,"sku":"PRO-067","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20µg","offer_id":43174257786964,"sku":"PRO-067","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":43174257819732,"sku":"PRO-067","price":3600.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-nhp2-human-PRO-067.png?v=1776703267"},{"product_id":"nhp2l1-human","title":"NHP2L1 Human","description":"\u003cp\u003eNHP2 non-histone chromosome protein 2-like Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eFA-1, SPAG12, SNRNP15-5, SNU13, 15.5K, U4\/U6.U5 tri-snRNP 15.5 kDa protein, NHP2 Non-Histone Chromosome protein 2-like 1 (S. cerevisiae), Sperm Specific Antigen 1, SSFA1, NHPX, FA1, OTK27, High Mobility Group-like Nuclear Protein 2 homolog 1.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"1µg","offer_id":43174258999380,"sku":"PRO-038","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10µg","offer_id":43174259032148,"sku":"PRO-038","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":43174259064916,"sku":"PRO-038","price":5200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-nhp2l1-human-PRO-038.png?v=1776703272"}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/collections\/Image_97c63a7a-c4f8-4c6d-8567-cf80698abcae.png?v=1700647703","url":"https:\/\/prospecbio.com\/collections\/nhp2.oembed","provider":"prospecbio","version":"1.0","type":"link"}