{"title":"Neutrophil Cytosolic Factor","description":"\u003ch2 class=\"highlited\" data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eAbout NCF \/ Neutrophil Cytosolic Factor:\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp data-mce-fragment=\"1\"\u003eNeutrophil Cytosolic Factor Protein, also referred to as NCF or p47phox is a protein found in humans which is encoded by the NCF1 gene.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eNCF Mechanism\u003c\/strong\u003e\u003cbr data-mce-fragment=\"1\"\u003eThe NCF protein is part of a process that develops the NADPH oxidase enzyme that plays a vital role in the human immune system.\u003cbr data-mce-fragment=\"1\"\u003eHowever, there is evidence that gene mutations can account for up to a quarter of all chronic granulomatous disease cases. This can affect the immune system, which also puts the individual at risk of recurrent infections.\u003cbr data-mce-fragment=\"1\"\u003eAnother health condition is Williams syndrome, and this is caused by an altogether absence of the NCF in chromosome 7.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eNeutrophil Cytosolic Factor Interactions\u003c\/strong\u003e\u003cbr data-mce-fragment=\"1\"\u003eStudies have shown that Neutrophil Cytosolic Factor interacts with at least three proteins. These are Moesin, Neutrophil Cytosolic Factor 4 and RELA.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eNCF Function\u003c\/strong\u003e\u003cbr data-mce-fragment=\"1\"\u003eWithout the NCF protein, the body would not stimulate phagocytes or begin creating NADPH oxidase. From here, several other compounds are generated, which include hydrogen peroxide and hypochlorous acid, two ingredients that are designed to kill infections.\u003cbr data-mce-fragment=\"1\"\u003eBy playing a part in creating this, NCF will contribute to eliminating foreign invaders to the body’s immune system. This allows you to remove possible infections and bacteria before it gets the chance the latch on, duplicate and spread throughout the body.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eNeutrophil Cytosolic Factor Structure\u003c\/strong\u003e\u003cbr data-mce-fragment=\"1\"\u003eNCF is a subunit of a group of proteins that creates an enzyme complex NADPH oxidase. Overall, 358 contain orthologs with the NCF1 human gene. These organisms include Rhesus monkeys, rats, chickens, zebrafish, and frogs.\u003cbr data-mce-fragment=\"1\"\u003eVariations of NCF are linked to several health conditions, including those listed above. Other conditions can include autoimmune disease, as the body is not capable of providing the right level of defense against infections.\u003c\/p\u003e","products":[{"product_id":"ncf1-human","title":"NCF1 Human","description":"\u003cp\u003eNeutrophil Cytosolic Factor 1 Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eNCF1A, NOXO2, p47phox, SH3PXD1A .\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"2µg","offer_id":43174183796820,"sku":"PRO-488","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10µg","offer_id":43174183829588,"sku":"PRO-488","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":43174183862356,"sku":"PRO-488","price":5200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-ncf1-human-PRO-488.png?v=1776703028"},{"product_id":"ncf4-human","title":"NCF4 Human","description":"\u003cp\u003eNeutrophil Cytosolic Factor 4 Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eNeutrophil cytosol factor 4, NCF-4, Neutrophil NADPH oxidase factor 4, SH3 and PX domain-containing protein 4, p40-phox, p40phox, NCF4, SH3PXD4, NCF, SH3PXD4.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"5µg","offer_id":43174184714324,"sku":"PRO-1258","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20µg","offer_id":43174184747092,"sku":"PRO-1258","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":43174184779860,"sku":"PRO-1258","price":3600.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-ncf4-human-PRO-1258.png?v=1776703034"}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/collections\/Image_bea42662-2a92-4dc3-a0b9-7f61dcea7ac3.png?v=1700647689","url":"https:\/\/prospecbio.com\/collections\/neutrophil-cytosolic-factor.oembed","provider":"prospecbio","version":"1.0","type":"link"}