{"title":"Neuronal Calcium Sensor","description":"\u003ch2 class=\"highlited\" data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eAbout NCS \/ Neuronal Calcium Sensor:\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp data-mce-fragment=\"1\"\u003eNeuronal Calcium Sensor Protein, otherwise referred to as NCS, is a substantial protein family that operates as calcium-dependent molecular switches. Members of the protein family include Frequenin (NCS1), VILIP-1 (Visinin-like-protein-1), HPCAL4 (Visinin-like-protein-2), hippocalcin, neurocalcin, and recoverin.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eNCS Mechanism\u003c\/strong\u003e\u003cbr data-mce-fragment=\"1\"\u003eResearch has shown that overexpression of members of the NCS family, particularly NCS1, can increase the chances of bipolar disorder and varying types of schizophrenia. Despite this, there is also a marked decrease in inflammatory bowel diseases.\u003cbr data-mce-fragment=\"1\"\u003eLinks have also been identified with Autism but also intelligence with the D2 dopamine receptors that encourage curiosity and increasing memory.\u003cbr data-mce-fragment=\"1\"\u003eNeuronal Calcium Sensor Proteins can regulate signal transduction while showing exceptional conservation of yeast to humans. The homolog fission yeast provides a crucial role in cell growth when experiencing extreme Ca2+ conditions.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eNeuronal Calcium Sensor Interactions\u003c\/strong\u003e\u003cbr data-mce-fragment=\"1\"\u003eThere are three distinct interactions you will find with NCS1 that include Kif21a, or kinesin family member 21A.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eNCS Function\u003c\/strong\u003e\u003cbr data-mce-fragment=\"1\"\u003eNCS boasts multiple functions all from a single protein. It provides an array of functionality with diverse performance that includes, but is not restricted to, gene transcription, the growth, and survival of neurons, regulating channels and receptions, and regulating enzymatic activity.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eNeuronal Calcium Sensor Structure\u003c\/strong\u003e\u003cbr data-mce-fragment=\"1\"\u003eEach member of the NCS family has 4 EF-hand motifs. Between these motifs, two or three can bind calcium. There is also an N-myristoyl group, although this is not shared by all family members.\u003cbr data-mce-fragment=\"1\"\u003eThe structure of the protein can vary depending on which family member you look at.\u003cbr data-mce-fragment=\"1\"\u003eCertain proteins are found in a wide range of organisms and have been reported in at least 264. Besides humans, the NCS protein is also present in cows, dogs, mosquitos, and fruit flies.\u003c\/p\u003e","products":[{"product_id":"ncs1-213-aa-human","title":"NCS1 213 a.a. Human","description":"\u003cp\u003eNeuronal Calcium Sensor 1 213 a.a. Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eNeuronal Calcium Sensor 1, Frequenin-Like Ubiquitous\nProtein, Frequenin-Like Protein, Frequenin Homolog, FREQ, FLUP, Frequenin\n(Drosophila) Homolog, Frequenin Homolog (Drosophila), FREQ, NCS-1, Neuronal\ncalcium sensor 1.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"5µg","offer_id":43174194249812,"sku":"PRO-2075","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20µg","offer_id":43174194282580,"sku":"PRO-2075","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":43174194315348,"sku":"PRO-2075","price":2700.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-ncs1-213-aa-human-PRO-2075.png?v=1776703050"},{"product_id":"ncs1-human","title":"NCS1 Human","description":"\u003cp\u003eNeuronal Calcium Sensor 1 Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eFrequenin homolog, FLUP, FREQ, Neuronal calcium sensor 1, Frequenin-like protein, Frequenin-like ubiquitous protein, NCS-1, NCS1, DKFZp761L1223.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"5µg","offer_id":43174196543572,"sku":"PRO-802","price":60.0,"currency_code":"USD","in_stock":true},{"title":"25µg","offer_id":43174196576340,"sku":"PRO-802","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":43174196609108,"sku":"PRO-802","price":2250.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-ncs1-human-PRO-802.png?v=1776444796"}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/collections\/Image_4f550c5d-526b-430d-b5b1-236d2e02845f.png?v=1700647692","url":"https:\/\/prospecbio.com\/collections\/neuronal-calcium-sensor.oembed","provider":"prospecbio","version":"1.0","type":"link"}