{"title":"N-Myc Downstream Regulated","description":"\u003ch2 class=\"highlited\" data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eAbout NDRG \/ N-Myc Downstream Regulated:\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp data-mce-fragment=\"1\"\u003eThe N-Myc downstream regulated gene (otherwise known as NDRG) has four proteins within its family – these are known as NDRG1-4. Even though evolution has changed much, no matter which way you turn or what you are studying, these proteins seem little changed by it, and so we can be relatively sure about them. There are some exciting developments in the studies of this gene, and there are many theories as to what they can actually do.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eNDRG Function\u003c\/strong\u003e\u003cbr data-mce-fragment=\"1\"\u003eThe very first member of the NDRG family was so called due to its manifestation being suppressed by the proto-oncogenes MYC and MYCN. When more family members were discovered, they could be linked to this initial finding due to the characterization of the α\/β hydrolase-fold motif. Of course, studies are ongoing, and this means that the exact cellular and even molecular makeup and function of each of the four members of the NDRG1-4 group is yet to be established.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eN-Myc Downstream Regulated Mutations\u003c\/strong\u003e\u003cbr data-mce-fragment=\"1\"\u003eDespite this, there is some evidence to show that mutations within the N-Myc downstream regulated gene are linked with a variety of electrophysiological and neurological syndromes. As well as this, there have been unusual demonstrations of tumor suppression and other functions that work against carcinogenesis, including cell proliferation, migrations, stress response, and invasion. It is essential to consider the NDRG family in terms of potential clinical application to do this; it could be a significant breakthrough in determining how to treat some cancers. Studies are ongoing into this and other potential applications for N-Myc downstream regulated genes.\u003c\/p\u003e","products":[{"product_id":"ndrg1-human","title":"NDRG1 Human","description":"\u003cp\u003eN-Myc Downstream Regulated 1 Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eProtein NDRG1, N-myc downstream-regulated gene 1 protein, Differentiation-related gene 1 protein, Reducing agents and tunicamycin-responsive protein, Nickel-specific induction protein Cap43, DRG-1, RTP, Rit42, NDRG1, CAP43, DRG1, GC4, NDR1, NMSL, TDD5, CMT4D, HMSNL, TARG1, PROXY1.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"10µg","offer_id":43174205980756,"sku":"PRO-724","price":60.0,"currency_code":"USD","in_stock":true},{"title":"50µg","offer_id":43174206013524,"sku":"PRO-724","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":43174206046292,"sku":"PRO-724","price":1800.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-ndrg1-human-PRO-724.png?v=1776444824"},{"product_id":"ndrg2-human","title":"NDRG2 Human","description":"\u003cp\u003eN-Myc Downstream Regulated 2 Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eN-myc downstream-regulated gene 2 protein, NDR1-related protein NDR2, protein NDRG2, NDRG family member 2, cytoplasmic protein Ndr1, syld709613 protein, KIAA1248, SYLD.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"5µg","offer_id":43174206799956,"sku":"PRO-1198","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20µg","offer_id":43174206832724,"sku":"PRO-1198","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":43174206865492,"sku":"PRO-1198","price":2700.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-ndrg2-human-PRO-1198.png?v=1776444829"},{"product_id":"ndrg3-human","title":"NDRG3 Human","description":"\u003cp\u003eN-Myc Downstream Regulated 3 Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eProtein NDRG3, N-myc downstream-regulated gene 3 protein, NDRG3, N-Myc Downstream Regulated 3.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"2µg","offer_id":43174207881300,"sku":"PRO-2100","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10µg","offer_id":43174207914068,"sku":"PRO-2100","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":43174207946836,"sku":"PRO-2100","price":5200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-ndrg3-human-PRO-2100.png?v=1776703076"}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/collections\/Image_4b24d871-c316-4bb7-8032-1cc6ffb08918.png?v=1700647694","url":"https:\/\/prospecbio.com\/collections\/n-myc-downstream-regulated.oembed","provider":"prospecbio","version":"1.0","type":"link"}