{"title":"Melanoma Antigen Family A","description":"\u003ch2 class=\"highlited\"\u003e\u003cspan\u003eAbout MAGE \/ Melanoma Antigen Family A:\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eMammalian members in the MAGE gene family\u003c\/strong\u003e\u003cbr\u003eThe MAGE gene family contains mammalian members, which were initially described as being fully silent within typical adult tissues. The only exception to this rule were male germ cells and, in some instances, the placenta. On the flip side, these genes were expressed in different tumor varieties.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eNon-mammalian members in MAGE-like genes\u003c\/strong\u003e\u003cbr\u003eIn addition to this, there are also MAGE-like genes that have been identified in species that are non-mammalian, for example, the Drosophila melanogaster or zebrafish. Despite the fact that there has not been the identification of any MAGE homologous sequences in Schizosaccharomyces pombe, Saccharomyces cerevisiae, or Caenorhabditis elegans, there has been the presence of MAGE sequences located in a number of different vegetal species. An example of this is Arabidopsis thaliana.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMAGE Structure\u003c\/strong\u003e\u003cbr\u003eThere is only one homology region that all of the family members share, and this is a stretch of roughly two hundred amino acids. These amino acids are known as the MAGE conserved domain. You will tend to find this situated near to the C-terminus, despite the fact that it can also be located in a more of a central location in some types of proteins. The MAGE conserved domain tends to be present as a solo copy, yet it can be duplicated in some specific proteins.\u003c\/p\u003e","products":[{"product_id":"magea3-human","title":"MAGEA3 Human","description":"\u003cp\u003eMelanoma Antigen Family A, 3 Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eCT1.3, MAGE3, HYPD, Melanoma Antigen family A, 3, MAGE-3 antigen, MAGEA6, Antigen MZ2-D, Melanoma-Associated antigen 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MAGE-3b.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"2µg","offer_id":43175097335892,"sku":"PRO-1113","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10µg","offer_id":43175097368660,"sku":"PRO-1113","price":145.0,"currency_code":"USD","in_stock":true},{"title":"100µg","offer_id":43175097401428,"sku":"PRO-1113","price":1200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-magea6-human-PRO-1113.png?v=1776702053"},{"product_id":"magea8-human","title":"MAGEA8 Human","description":"\u003cp\u003eMelanoma Antigen Family A, 8 Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eMelanoma Antigen Family A8, MAGE-8 Antigen, MAGE8, Cancer\/Testis Antigen 1.8, CT1.8, Cancer\/Testis Antigen Family 1, Member 8, Cancer\/Testis Antigen Family 1, Melanoma-Associated Antigen 8, Melanoma Antigen Family A, 8, Member 8, 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