{"title":"GDP Dissociation Inhibitor","description":"\u003ch2 class=\"highlited\"\u003e\u003cspan\u003eAbout GDI \/ GDP Dissociation Inhibitor:\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp\u003eThe C-terminal, known as geranylgeranylation, is a vital mechanism for the proper function of the GDI and its association. It is a post-translational modification catalysed by the Rab enzyme, also known as geranylgeranyl transferase (Rab-GGTase).\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eGDI Structure\u003c\/strong\u003e\u003cbr\u003eThe Rab Escort protein, as it is colloquially known, is an enzyme that contains a catalytic heterodimer and an accessory component. It presents newly synthesised Rab proteins to the catalytic component to form stable complex prenylated proteins.\u003cbr\u003eThe structure of the Rab GDI protein is crystal. It has a resolution of 1.81 Angstrom. It is typically composed of two parts, a large and complex multi-sheet domain and a smaller alpha, helical domain. The most important part of the structure is the apex of the molecule, which plays a crucial role in the binding of Rab proteins.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eGDP Dissociation Inhibitor Mechanism\u003c\/strong\u003e\u003cbr\u003eThe Rab GDP dissociation inhibitor is similar to the mechanism of the REP-1 mediated membrane association of Rab 5. This pair of inhibitors share other properties, too, like their ability to inhibit the release of GDP and to remove Rab protein and membranes. Like most proteins, the Rab GDP doesn't function alone and interacts with molecular machines made of numerous content proteins.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eGDI Function\u003c\/strong\u003e\u003cbr\u003eGDP dissociation inhibitors regulate the exchange reaction of members of the Rab family. They are small binding proteins involved in the vesicular trafficking of molecules between organelles.\u003cbr\u003eRab GTPases is crucial to the exchange. It cycles between the cytosolic compartment and the membrane. It is bound to a protein in the compartment and interacts with a receptor in the exchange to catalyse the process.\u003c\/p\u003e","products":[{"product_id":"gdi1-human","title":"GDI1 Human","description":"\u003cp\u003eGDP Dissociation Inhibitor 1 Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eRab GDP dissociation inhibitor alpha, Rab GDI alpha, GDP Dissociation Inhibitor 1, GDI1, Guanosine diphosphate dissociation inhibitor 1, GDI-1, Oligophrenin-2, XAP-4, GDIL, OPHN2, RABGDIA, XAP4, MRX41, MRX48, 1A, RABGD1A.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"2µg","offer_id":43174843416660,"sku":"PRO-2023","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10µg","offer_id":43174843449428,"sku":"PRO-2023","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":43174843482196,"sku":"PRO-2023","price":5200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-gdi1-human-PRO-2023.png?v=1776695103"},{"product_id":"gdi2-human","title":"GDI2 Human","description":"\u003cp\u003eGDP Dissociation Inhibitor 2 Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eGDP Dissociation Inhibitor 2, GDI2, RABGDIB, Guanosine Diphosphate Dissociation Inhibitor 2 , Rab GDI Beta , GDI-2, Epididymis Secretory Sperm Binding Protein Li 46e, Rab GDP Dissociation Inhibitor Beta , Rab GDP-Dissociation , HEL-S-46e.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"2µg","offer_id":43174844399700,"sku":"PRO-1948","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10µg","offer_id":43174844432468,"sku":"PRO-1948","price":145.0,"currency_code":"USD","in_stock":true},{"title":"100µg","offer_id":43174844465236,"sku":"PRO-1948","price":1200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-gdi2-human-PRO-1948.png?v=1776695107"}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/collections\/Image_70564a7a-afa6-4056-96ae-592343375f5b.png?v=1700647461","url":"https:\/\/prospecbio.com\/collections\/gdp-dissociation-inhibitor.oembed","provider":"prospecbio","version":"1.0","type":"link"}