{"title":"GABA(A) Receptor-Associated Protein","description":"\u003ch2 class=\"highlited\"\u003e\u003cspan\u003eAbout GABARAP \/ GABA(A) Receptor-Associated Protein:\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp\u003eGamma-aminobutyric acid receptor-associated protein (GABA) A is a protein found in humans, vertebrates, and invertebrates. They are ligand-gates chloride channels involved in inhibitory neurotransmission. It is encoded by the GABARAP gene in the human genome.\u003cbr\u003eGABARP was initially identified and its function was discovered and clarified back in 1957. An experienced team of Canadian researchers discovered that the compound responsible for the inhibitory activity in crayfish was, in fact, GABA. The first time this activity had ever been accounted for. This was subsequently confirmed by a number of other studies.\u003cbr\u003eThey play an important role in the human central nervous system. Research has shown that dysfunction of GABARAP in the localization of cell membranes, can be associated with a range of server psychiatric disorders that have a confirmed diagnosis.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eGABARAP Function\u003c\/strong\u003e\u003cbr\u003eThe main function of GABARAP is an inhibitory neurotransmitter. It is found in the brain of humans as well as other vertebrates and invertebrates. By binding to the GABA receptors, it mediates neuronal inhibition in humans, vertebrates, and invertebrates.\u003cbr\u003eMutations of the gene that encodes GABARAP have been associated with seizure activity and epilepsy.\u003cbr\u003eGABA(A) subunits go to assemble type A GABARP from the pentameric chloride channels.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eGABA(A) Receptor-Associated Protein Interactions\u003c\/strong\u003e\u003cbr\u003eThere are a number of documented and confirmed GABARP interactions that exist. In tests and through computationally derived observations, GABARAP has been seen to interact with the following:\u003cbr\u003e●Transferrin receptor protein 1 (TFRC)\u003cbr\u003e●ULK1\u003cbr\u003e●Gamma-aminobutyric acid receptor subunit gamma-2 (GABRG2)\u003cbr\u003eResearch is ongoing as to a number of other potential interactions.\u003c\/p\u003e","products":[{"product_id":"gabarap-human","title":"GABARAP Human","description":"\u003cp\u003eGABA(A) Receptor-Associated Protein Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eGBRAP, MM46, GABA(A) receptor-associated protein, Gamma-aminobutyric acid receptor-associated protein, GABARAP, FLJ25768, MGC120154, MGC120155, FLC3B.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"10µg","offer_id":43174774341716,"sku":"PRO-775","price":60.0,"currency_code":"USD","in_stock":true},{"title":"50µg","offer_id":43174774374484,"sku":"PRO-775","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":43174774407252,"sku":"PRO-775","price":2250.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-gabarap-human-PRO-775.png?v=1776694773"},{"product_id":"gabarapl1-human","title":"GABARAPL1 Human","description":"\u003cp\u003eGABA(A) Receptor-Associated Protein Like 1 Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eGamma-aminobutyric acid receptor-associated protein-like 1, Early estrogen-regulated protein, GABA(A) receptor-associated protein-like 1, Glandular epithelial cell protein 1, GEC-1, GABARAPL1, GEC1, ATG8, APG8L, ATG8B, ATG8L, APG8-LIKE.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"5µg","offer_id":43174775652436,"sku":"PRO-048","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20µg","offer_id":43174775685204,"sku":"PRO-048","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":43174775717972,"sku":"PRO-048","price":3600.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-gabarapl1-human-PRO-048.png?v=1776694777"},{"product_id":"gabarapl2-human","title":"GABARAPL2 Human","description":"\u003cp\u003eGABA(A) Receptor-Associated Protein Like 2 Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eGABA(A) receptor-associated protein-like 2, GATE-16, GEF2, ATG8, ATG8C, Ganglioside expression factor 2, General protein transport factor p16, Golgi-associated ATPase enhancer of 16 kDa, MAP1 light chain 3-related protein, gamma-aminobutyric acid receptor-associated protein-like 2, MAP1 light chain 3 related protein, FLC3A.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"2µg","offer_id":43174776406100,"sku":"PRO-079","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10µg","offer_id":43174776438868,"sku":"PRO-079","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":43174776471636,"sku":"PRO-079","price":5200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-gabarapl2-human-PRO-079.png?v=1776694781"}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/collections\/Image_2b42b36d-a250-49f7-b148-b610524f4dfe.png?v=1700647448","url":"https:\/\/prospecbio.com\/collections\/gaba-a-receptor-associated-protein.oembed","provider":"prospecbio","version":"1.0","type":"link"}