{"title":"Dynein Light Chain","description":"\u003ch2 class=\"highlited\"\u003e\u003cspan\u003eAbout Dynein Light Chain:\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp\u003eDynein was first discovered and then named in 1963 by Ian R. Gibbons. It consists of various chains. These are heavy, intermediate, light intermediate and light. They are commonly divided into two different groups. These are cytoplasmic and axonemal dyneins. Cytoplasmic dynein is responsible for cell mitosis and intracellular transport and axonemal dynein is involved in ciliary\/flagellar beating.\u003cbr\u003eDynein Light Chain (DNAL, DYNL) is encoded by the DYNLL1 gene in humans and is classed as a cytoplasmic protein.\u003cbr\u003eThe name dynein light chain itself is derived from the original description of DYNL in the dynein motor complex as a small molecular weight.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDynein Light Chain Structure\u003c\/strong\u003e\u003cbr\u003eThe structure of DNAL\/DYNL consists of:\u003cbr\u003e1.Heavy - 530 kDA\u003cbr\u003e2.Intermediate - 74 kDA\u003cbr\u003e3.Light intermediate - 33-59 kDA\u003cbr\u003e4.Light chain - 10-20 kDA\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDynein Light Chain Function\u003c\/strong\u003e\u003cbr\u003eDyneins have a molecular mass of approximately 1,200 kD. They are large enzyme complexes. DNAL\/DYNL is heavily involved in intracellular motility and transport. The light chain exists as part of this and inhibits neuronal nitric oxide synthase activity.\u003cbr\u003eThrough its oxide synthase activity, it may be responsible for the regulation of various biological processes.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDynein Light Chain Interactions\u003c\/strong\u003e\u003cbr\u003eSince its discovery, DYNL has been observed to interact with the following:\u003cbr\u003e●Bcl-2-like protein 11 (BCL2L1)\u003cbr\u003e●PSD-95 (postsynaptic density protein 95) - (DLG4)\u003cbr\u003e●Disks large-associated protein 1 - (DLGAP1)\u003cbr\u003e●Cytoplasmic dynein 1 intermediate chain 1 - (DYNC1I1)\u003cbr\u003e●nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha) -(IκBα)\u003cbr\u003e●Myosin-Va - (MYO5A)\u003cbr\u003e●Nuclear respiratory factor 1 - (NRF1)\u003cbr\u003e●Serine\/threonine-protein kinase - (PAK1)\u003cbr\u003e●Tumour suppressor p53-binding protein 1 - (TP53BP1)\u003c\/p\u003e","products":[{"product_id":"dnal1-human","title":"DNAL1 Human","description":"\u003cp\u003eDynein Axonemal Light Chain 1 Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eDynein light chain 1, axonemal, C14orf168, CILD16, DNAL1.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"5µg","offer_id":43174209847380,"sku":"PRO-1357","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20µg","offer_id":43174209880148,"sku":"PRO-1357","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":43174209912916,"sku":"PRO-1357","price":2700.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-dnal1-human-PRO-1357.png?v=1776682848"},{"product_id":"dnal4-human","title":"DNAL4 Human","description":"\u003cp\u003eDynein Axonemal Light Chain 4 Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eDynein light chain 4 axonemal, DNAL4, PIG27.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"5µg","offer_id":43174210895956,"sku":"PRO-227","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20µg","offer_id":43174210928724,"sku":"PRO-227","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":43174210961492,"sku":"PRO-227","price":2700.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-dnal4-human-PRO-227.png?v=1776682853"},{"product_id":"dnali1-human","title":"DNALI1 Human","description":"\u003cp\u003eDynein Axonemal Light Intermediate Chain 1 Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eDynein, Axonemal, Light Intermediate Chain 1, DJ423B22.5\n(Axonemal Dynein Light Chain (Hp28)), Inner Dynein Arm Light Chain Axonemal,\nhp28, P28, Homolog Of Clamydomonas, Axonemal Dynein Light Intermediate\nPolypeptide 1, dJ423B22.5, Inner Dynein Arm,\nHomolog Of Clamydomonas, Dynein, Axonemal, Light Intermediate Polypeptide 1.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"5µg","offer_id":43174211518548,"sku":"PRO-1756","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20µg","offer_id":43174211551316,"sku":"PRO-1756","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":43174211584084,"sku":"PRO-1756","price":2700.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-dnali1-human-PRO-1756.png?v=1776442166"},{"product_id":"dynll1-human","title":"DYNLL1 Human","description":"\u003cp\u003eDynein Light Chain LC8 Type-1 Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003ePIN, DLC1, DLC8, DNCL1, DNCLC1, Dynein Light Chain LC8-type 1, Dynein Cytoplasmic Light polypeptide 1, Protein Inhibitor of Neuronal Nitric Oxide Synthase\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"5µg","offer_id":43174253264980,"sku":"PRO-262","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20µg","offer_id":43174253297748,"sku":"PRO-262","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":43174253330516,"sku":"PRO-262","price":2700.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-dynll1-human-PRO-262.png?v=1776682998"},{"product_id":"dynll2-human","title":"DYNLL2 Human","description":"\u003cp\u003eDynein Light Chain LC8 Type-2  Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eDynein light chain LC8-type 2, DNCL1B, Dlc2, MGC17810, RSPH22, 8kDa dynein light chain b, DLC8b, dynein light chain 2 cytoplasmic, radial spoke 22 homolog.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"5µg","offer_id":43174254313556,"sku":"PRO-235","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20µg","offer_id":43174254346324,"sku":"PRO-235","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":43174254379092,"sku":"PRO-235","price":2700.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-dynll2-human-PRO-235.png?v=1776683002"},{"product_id":"dynlrb1-human","title":"DYNLRB1 Human","description":"\u003cp\u003eDynein Light Chain Roadblock-Type 1 Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eBITH, BLP, DNCL2A, DNLC2A, ROBLD1, HSPC162.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"2µg","offer_id":43174255165524,"sku":"PRO-489","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10µg","offer_id":43174255198292,"sku":"PRO-489","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":43174255231060,"sku":"PRO-489","price":5200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-dynlrb1-human-PRO-489.png?v=1776683008"},{"product_id":"dynlrb2-human","title":"DYNLRB2 Human","description":"\u003cp\u003eDynein Light Chain Roadblock-Type 2 Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eDynein light chain roadblock-type 2, Dynein light chain 2B cytoplasmic, Roadblock domain-containing protein 2, DYNLRB2, DNCL2B, DNLC2B, ROBLD2, MGC62033.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"5µg","offer_id":43174255984724,"sku":"PRO-174","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20µg","offer_id":43174256017492,"sku":"PRO-174","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":43174256050260,"sku":"PRO-174","price":2700.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-dynlrb2-human-PRO-174.png?v=1776683012"},{"product_id":"dynlt1-human","title":"DYNLT1 Human","description":"\u003cp\u003eDynein, Light Chain, Tctex-Type 1 Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eDynein light chain Tctex-type 1, Protein CW-1, T-complex testis-specific protein 1 homolog, DYNLT1, TCTEL1, TCTEX-1, TCTEX1, CW-1.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"5µg","offer_id":43174256934996,"sku":"PRO-757","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20µg","offer_id":43174256967764,"sku":"PRO-757","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":43174257000532,"sku":"PRO-757","price":2700.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-dynlt1-human-PRO-757.png?v=1776683016"},{"product_id":"dynlt3-human","title":"DYNLT3 Human","description":"\u003cp\u003eDynein, Light Chain, Tctex-Type 3 Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eDynein light chain Tctex-type 3, t-complex-associated-testis-expressed 1-like, TCTE1XL, Protein 91\/23, TCTEX1L, TCTE1L, RP3.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"2µg","offer_id":43174257655892,"sku":"PRO-1197","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10µg","offer_id":43174257688660,"sku":"PRO-1197","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":43174257721428,"sku":"PRO-1197","price":5200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-dynlt3-human-PRO-1197.png?v=1776683021"}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/collections\/Image_80efd3f1-8bd7-4b95-92c7-1c104c783c26.png?v=1700646653","url":"https:\/\/prospecbio.com\/collections\/dynein-light-chain.oembed","provider":"prospecbio","version":"1.0","type":"link"}