{"title":"Deaminase","description":"\u003ch3 class=\"highlited\"\u003e\u003cspan\u003eAbout Deaminase:\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp\u003eDeaminase is one of the enzymes involved in deamination, a process that, through hydrolysis, removes an amino group from a molecule. The primary way that deaminase removes an amino group is from extra proteins that occur in the liver or kidneys.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDeaminase Function\u003c\/strong\u003e\u003cbr\u003eDeamination plays an important role in the body, helping to eliminate waste, and nitrogen waste, in particular. Deaminase removes the amino group and the nitrogen waste is converted to ammonia and then removed from the body through urination. The amino groups that are removed bond with a hydrogen molecule to form ammonia and a separate process then combines the ammonia with carbon dioxide, turning it into either urea or uric acid.\u003cbr\u003eDeaminase also plays a role in converting the amino groups removed from proteins into different sources that the body can use. These include resources such as hydrogen and carbon, which are important to various different functions in the body. Ultimately, deaminase is important for keeping the body balanced and ensuring excess amounts of substances don't build up.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDeaminase Mechanism\u003c\/strong\u003e\u003cbr\u003eThere are different types of deaminase which perform various roles in the body. For example, APOBEC3G, or A3G, plays a role in the cellular defence against HIV and its progression. The antiviral mechanisms of A3G can create mutations in the viral genome of HIV.\u003cbr\u003eAlthough the main place where deamination occurs is in the liver, it also takes place in the kidneys. Glutamic acid is the most significant amino acid involved in deamination. Other amino acids are mostly deaminated through transamination and deamination of glutamate where glutamate recycles. Excess glutamate undergoes deamination in the kidneys, and glutamate dehydrogenase catalyzes the process. Histidase forms trans-urocanic acid by removing the amino group from histidine. This enzyme is found in the liver and skin. Deamination in the kidneys also produces ammonia, which is disposed of.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDeaminase Interactions\u003c\/strong\u003e\u003cbr\u003eAdenosine or adenine deaminase (ADA) is involved in purine metabolism, breaking down adenosine from food. It is also necessary for the turnover of nucleic acids in tissues. It helps to develop and maintain the human immune system. ADA deaminates adenosine by substituting the amino group for a keto group and converting it into nucleoside inosine. ADA also converts deoxyadenosine to deoxyinosine.\u003c\/p\u003e","products":[{"product_id":"ada-human","title":"ADA Human","description":"\u003cp\u003eAdenosine Deaminase Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eAdenosine deaminase, Adenosine aminohydrolase, ADA1, EC 3.5.4.4.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"2µg","offer_id":43173998198868,"sku":"ENZ-147","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10µg","offer_id":43173998231636,"sku":"ENZ-147","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":43173998264404,"sku":"ENZ-147","price":5200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-ada-human-ENZ-147.png?v=1776676373"},{"product_id":"adal-human","title":"ADAL Human","description":"\u003cp\u003eAdenosine Deaminase-Like Human Recombinant\u003c\/p\u003e\n\n\u003cdiv 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TAD2.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"2µg","offer_id":43174003277908,"sku":"ENZ-561","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10µg","offer_id":43174003310676,"sku":"ENZ-561","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":43174003343444,"sku":"ENZ-561","price":5200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-adat2-human-ENZ-561.png?v=1776676395"},{"product_id":"aicda-human","title":"AICDA Human","description":"\u003cp\u003eActivation-Induced Cytidine Deaminase Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eSingle-stranded DNA cytosine deaminase, Activation-induced cytidine deaminase, Cytidine aminohydrolase, AICDA, AID, ARP2, CDA2, HIGM2.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"5µg","offer_id":43174047481940,"sku":"ENZ-651","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20µg","offer_id":43174047514708,"sku":"ENZ-651","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":43174047547476,"sku":"ENZ-651","price":2700.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-aicda-human-ENZ-651.png?v=1776440151"},{"product_id":"dctd-human","title":"DCTD Human","description":"\u003cp\u003edCMP Deaminase Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eDeoxycytidylate deaminase, EC 3.5.4.12, dCMP Deaminase, DCTD, 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