{"title":"Chloride Intracellular Channel","description":"\u003ch2 class=\"highlited\"\u003e\u003cspan\u003eAbout CLIC \/ Chloride Intracellular Channel:\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp\u003eCLIC1 stands for chloride intracellular channel protein 1, which is a type of protein found within humans.\u003cbr\u003eChloride channels are a varied collection of proteins that are responsible for regulating critical cellular processes. Some of the processes that these proteins are responsible for include regulating the volume of calls, maintaining intracellular PH, transepithelial transport, and stabilizing the potential of the cell membrane.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCLIC Function\u003c\/strong\u003e\u003cbr\u003eCLIC1 is a member of the protein family p64. This means that the protein principally localizes to the nucleus of the cell, exhibiting both plasma and nuclear membrane chloride ion channel activity.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eChloride Intracellular Channel Interactions\u003c\/strong\u003e\u003cbr\u003eIn terms of interaction, this protein has been proven to interact with TRAPPC2. For those whoa re unaware, TRAPPC2 stands for trafficking protein particle complex subunit 2. This protein is believed to be part of a big multisubunit complex that is involved in the fusing and targeting of endoplasmic reticulum-to-Golgi transport vesicles with their acceptor compartment.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCLIC Structure\u003c\/strong\u003e\u003cbr\u003eCLICs have been proven to exist in both integral and soluble membrane forms.\u003cbr\u003eCLIC1 can be interested in membranes, forming channels of chloride ion. The channel activity is dependent on the pH.\u003cbr\u003eInserting into the membrane appears to be redox-regulated and this may only happen under conditions of oxidation.\u003cbr\u003eCLIC1 in the soluble form is structurally homologous and monomeric to the superfamily of glutathione S-transferase, with a redox-active site that resembles glutaredoxin.\u003c\/p\u003e","products":[{"product_id":"clic1-human","title":"CLIC1 Human","description":"\u003cp\u003eChloride Intracellular Channel 1 Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eACBP, ACBD1, CCK-RP, EP, CLIC1, G6, NCC27, Nuclear chloride ion channel 27, Chloride channel ABP, Regulatory nuclear chloride ion channel protein, hRNCC, Chloride intracellular channel protein 1.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"5µg","offer_id":43175066861652,"sku":"PRO-833","price":60.0,"currency_code":"USD","in_stock":true},{"title":"25µg","offer_id":43175066894420,"sku":"PRO-833","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":43175066927188,"sku":"PRO-833","price":2250.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-clic1-human-PRO-833.png?v=1776681497"},{"product_id":"clic2-human","title":"CLIC2 Human","description":"\u003cp\u003eChloride Intracellular Channel 2 Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eChloride intracellular channel protein 2, XAP121, CLIC2, CLIC2b, XAP121.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"5µg","offer_id":43175067811924,"sku":"PRO-198","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20µg","offer_id":43175067844692,"sku":"PRO-198","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":43175067877460,"sku":"PRO-198","price":2700.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-clic2-human-PRO-198.png?v=1776681501"},{"product_id":"clic4-human","title":"CLIC4 Human","description":"\u003cp\u003eChloride Intracellular Channel 4 Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eChloride intracellular channel protein 4, Intracellular chloride ion channel protein p64H1, CLIC4, H1, huH1, p64H1, CLIC4L, MTCLIC, FLJ38640, DKFZp566G223.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"5µg","offer_id":43175068631124,"sku":"PRO-173","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20µg","offer_id":43175068663892,"sku":"PRO-173","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":43175068696660,"sku":"PRO-173","price":3600.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-clic4-human-PRO-173.png?v=1776681506"},{"product_id":"clns1a-human","title":"CLNS1A Human","description":"\u003cp\u003eChloride Channel, Nucleotide-Sensitive, 1A Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eCLNS1A, CLCI, ICLN, CLNS1B, Methylosome subunit pICln, Chloride channel, nucleotide sensitive 1A, Chloride conductance regulatory protein ICln, Chloride ion current inducer protein, Reticulocyte pICln.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"5µg","offer_id":43175071219796,"sku":"PRO-1277","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20µg","offer_id":43175071252564,"sku":"PRO-1277","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":43175071285332,"sku":"PRO-1277","price":2700.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-clns1a-human-PRO-1277.png?v=1776681519"}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/collections\/Image_09e0661d-9228-4bc3-8855-cbacc3e1898b.png?v=1700646577","url":"https:\/\/prospecbio.com\/collections\/chloride-intracellular-channel.oembed","provider":"prospecbio","version":"1.0","type":"link"}