{"title":"CCR4-NOT Transcription Complex","description":"\u003ch2 class=\"highlited\"\u003e\u003cspan\u003eAbout CNOT \/ CCR4-NOT Transcription Complex:\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp\u003eThe CCR4-NOT Transcription Complex is a complex protein with multiple units that regulates gene expression.\u003cbr\u003eThe acronym CCR4-NOT stands for Carbon Catabolite Repression—Negative On TATA-less. It is responsible for the mRNAs (Messenger RNA) life cycle (from the nucleus to the cytoplasm). The eukaryotes conserve the CCR4-NOT and ensure that the processes are well-defined by regulating them.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCNOT Mechanism\u003c\/strong\u003e\u003cbr\u003eTo achieve its functionality, the CCR4-NOT utilizes various repression, initiation, translation, and regulatory measures. Different processes are initiated during different periods to ensure an endless process loop. Its presence in the nucleus and cytoplasm enables the CCR4 to regulate the transcription and also translate the ribosomes.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCCR4-NOT Transcription Complex Structure\u003c\/strong\u003e\u003cbr\u003eCCR4 consists of multiple units of conserved core proteins and scaffold proteins, which result in different functions of the protein in their different combinational amounts.\u003cbr\u003eThe extensive research of the CCR4's structures does not reveal the complex structure of the CCR4, but using the currently available designs makes it possible to work towards its gene expression functionality in the system.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCNOT Interactions\u003c\/strong\u003e\u003cbr\u003eThe interactions of the CCR4 with transcription factors will result in transcription activation or repression. It is dependent on the promoters in the yeast, receptors, inhibitors, and amount of eukaryotes.\u003cbr\u003eThese interactions will also affect the elongation and deletion of the mRNAs.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCCR4-NOT Transcription Complex Function\u003c\/strong\u003e\u003cbr\u003eThe CCR4 specializes in ensuring the mRNAs' production in the nucleus follows through the right processes, transcription initiation and elongation, quality control, mRNA export, and the decay and decompositions of the RNA. An insight into the functionality of the RA will give you a hint on the importance of CCR4.\u003c\/p\u003e","products":[{"product_id":"cnot7-mouse","title":"CNOT7 Mouse","description":"\u003cp\u003eCCR4-NOT Transcription Complex, Subunit 7 Mouse Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eCCR4-NOT transcription complex subunit 7, Cnot7, Caf1, Pop2, AU022737.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"5µg","offer_id":43175107035220,"sku":"PRO-908","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20µg","offer_id":43175107067988,"sku":"PRO-908","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":43175107100756,"sku":"PRO-908","price":2700.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-cnot7-mouse-PRO-908.png?v=1776681694"},{"product_id":"cnot8-human","title":"CNOT8 Human","description":"\u003cp\u003eCCR4-NOT Transcription Complex, Subunit 8 Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eCCR4-NOT transcription complex subunit 8, CAF1, CALIF, hCAF1, POP2, CAF1-like protein, CAF2, CCR4-associated factor 8, Caf1b, CNOT8.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"5µg","offer_id":43175108444244,"sku":"PRO-1517","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20µg","offer_id":43175108477012,"sku":"PRO-1517","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":43175108509780,"sku":"PRO-1517","price":3600.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-cnot8-human-PRO-1517.png?v=1776681699"}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/collections\/Image_1bc364ae-0b4a-42d3-abb7-844134f29ed8.png?v=1700646583","url":"https:\/\/prospecbio.com\/collections\/ccr4-not-transcription-complex.oembed","provider":"prospecbio","version":"1.0","type":"link"}