{"title":"Caspase Recruitment Domain Family","description":"\u003ch2 class=\"highlited\"\u003e\u003cspan\u003eAbout CARD \/ Caspase Recruitment Domain Family:\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp\u003eCARD is an interactive protein belonging to the death domain superfamily.\u003cbr\u003eThe DD superfamily is among the most prominent families of the interactive protein modules and comprises the death domain, death effector domain, and pyrin domain. CARD gets used in the inflammation and apoptosis processes.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCARD Mechanism\u003c\/strong\u003e\u003cbr\u003eThe DD subfamily uses proteases as a precursor of the nucleated cells. It also utilizes the two-step signaling pathway. CARD uses different mechanisms to convert the apoptotic stimuli to proteolytic activity.\u003cbr\u003eThese activities are then responsible for multiplying the prostrate substrate proteolysis for efficient apoptosis.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCaspase Recruitment Domain Family Interactions\u003c\/strong\u003e\u003cbr\u003eActivation of the caspase-9, which was the first structure to exhibit the DD protein interaction interface, requires a specific assembly by the apoptosome. Its result is complex CARD-CARD heterodimeric structures. Consequently, different dimeric forms are stemming from the initial setup, thus enhancing its functionality.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCARD Function\u003c\/strong\u003e\u003cbr\u003eThe subfamily domains' primary function is to monitor and regulate the inflammation and apoptosis processes in mammals. Typically, the inflammation is due to bacterial or viral infections. It is also responsive to some types of stress signals.\u003cbr\u003eCollectively, CARD domains work to illuminate the autoimmune system. Having a deficiency in CARD proteins can cause you a dip in your immunodeficiency – further elaborating its role in the immune system.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCaspase Recruitment Domain Family Structure\u003c\/strong\u003e\u003cbr\u003eYou can find the CARD domain in various proteins like mitochondrial proteins, helicases, or kinases. The most common type is the six-helix structure (a conservative bundle fold), a significant component in your immune response system.\u003cbr\u003eThe CARD family's complex oligomeric structure is a recent entry in the CARD family due to recent research of the RIG-I and MAVS complex.\u003cbr\u003eCARD plays a significant role in your responsiveness to various stimuli and inflammations.\u003c\/p\u003e","products":[{"product_id":"card17-human","title":"CARD17 Human","description":"\u003cp\u003eCaspase Recruitment Domain Family, Member 17 Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eCARD17, Caspase Recruitment Domain Family, Member 17, Caspase recruitment domain-containing protein 17, INCA, Caspase-1 inhibitor INCA, Inhibitory caspase recruitment domain protein.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"5µg","offer_id":43174646054996,"sku":"PRO-1688","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20µg","offer_id":43174646087764,"sku":"PRO-1688","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":43174646120532,"sku":"PRO-1688","price":2700.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-card17-human-PRO-1688.png?v=1776679095"},{"product_id":"card18-human","title":"CARD18 Human","description":"\u003cp\u003eCaspase Recruitment Domain Family, Member 18 Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eCaspase recruitment domain family member 18, ICEBERG, pseudo-ICE, UNQ5804, Caspase-1 inhibitor Iceberg, ICEBERG caspase-1 inhibitor.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"2µg","offer_id":43174646841428,"sku":"PRO-1061","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10µg","offer_id":43174646874196,"sku":"PRO-1061","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":43174646906964,"sku":"PRO-1061","price":5200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-card18-human-PRO-1061.png?v=1776679100"}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/collections\/Image_8749d72d-9938-4679-bd91-2d48f61efc97.png?v=1700646475","url":"https:\/\/prospecbio.com\/collections\/caspase-recruitment-domain-family.oembed","provider":"prospecbio","version":"1.0","type":"link"}