{"title":"Baculoviral IAP Repeat-Containing","description":"\u003ch2 class=\"highlited\"\u003e\u003cspan\u003eAbout BIRC \/ Baculoviral IAP Repeat-Containing Protein:\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp\u003ePut simply, Baculoviral IAP Repeat-Containing Protein is a human protein that is made up of the BIRC gene. It is a member of the inhibitor of apoptosis family and works to interfere with the activation of caspases - a family of protease enzymes that plan essential roles in programmed cell death. BIRC proteins function to modify enzymes that target proteins for proteasomal degradation, a chemical reaction that breaks down peptide bonds.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBIRC Mechanisms\u003c\/strong\u003e\u003cbr\u003eThe protein that is encoded by the gene binds to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 for example. They have also been found to have spliced transcript variants encoding different isoforms.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBaculoviral IAP Repeat-Containing Protein interactions\u003c\/strong\u003e\u003cbr\u003eBaculoviral IAP Repeat-Containing Protein has been shown to interact with RIPK1, CASP9, UBE2D2, TRAF1 and TRAF2.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBIRC function\u003c\/strong\u003e\u003cbr\u003eBIRC2 plays a role in tumour necrosis by allowing the activaation of inflammatory and pro-survival genes and triggering the degradation of ikB alpha. BIRC1 (also known as NAIP) acts as a mediator in pathological conditions to neuronal survival and can help to prevent motor-neuron apoptosis.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBaculoviral IAP Repeat-Containing Protein structure\u003c\/strong\u003e\u003cbr\u003eThe BIRC protein contains three main BIR domains - a RING finger domain, a CARD domain and a UBA domain. The RING finger domain is a protein structural domain of zinc finger, CARD domains are interaction motifs found in proteins such as those with processes which relate to inflammation and apoptosis and UBA is a protein domain that interacts non-covalently through protein-protein interactions with ubiquitin.\u003c\/p\u003e","products":[{"product_id":"birc5-human","title":"BIRC5 Human","description":"\u003cp\u003eBaculoviral IAP Repeat-Containing 5 Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eBIRC-5, Baculoviral IAP repeat-containing protein 5, API4, EPR-1, Apoptosis inhibitor survivin, Apoptosis inhibitor 4, BIRC5, IAP4, Survivin.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"5µg","offer_id":43174420512852,"sku":"PRO-613","price":60.0,"currency_code":"USD","in_stock":true},{"title":"25µg","offer_id":43174420545620,"sku":"PRO-613","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":43174420578388,"sku":"PRO-613","price":2700.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-birc5-human-PRO-613.png?v=1776677846"},{"product_id":"birc7-human","title":"BIRC7 Human","description":"\u003cp\u003eBaculoviral IAP Repeat-Containing 7 Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eBaculoviral IAP repeat-containing protein 7, KIAP, MLIAP, RNF50, ML-IAP, LIVIN, Kidney inhibitor of apoptosis protein, Melanoma inhibitor of apoptosis protein, RING finger protein 50, BIRC7.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"5µg","offer_id":43174421397588,"sku":"PRO-612","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20µg","offer_id":43174421430356,"sku":"PRO-612","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":43174421463124,"sku":"PRO-612","price":3600.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-birc7-human-PRO-612.png?v=1776677855"},{"product_id":"birc7-human-1-280-aa","title":"BIRC7 Human, (1-280 a.a.)","description":"\u003cp\u003eBaculoviral IAP Repeat-Containing 7 (1-280 a.a.) Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eBaculoviral IAP repeat-containing protein 7, KIAP, MLIAP, RNF50, ML-IAP, LIVIN, Kidney inhibitor of apoptosis protein, Melanoma inhibitor of apoptosis protein, RING finger protein 50, BIRC7.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"2µg","offer_id":43174422511700,"sku":"PRO-1042","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10µg","offer_id":43174422544468,"sku":"PRO-1042","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":43174422577236,"sku":"PRO-1042","price":5200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-birc7-human-1-280-aa-PRO-1042.png?v=1776677850"}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/collections\/Image_384d3945-db3b-4989-a4b7-d4219dded248.png?v=1700646428","url":"https:\/\/prospecbio.com\/collections\/baculoviral-iap-repeat-containing.oembed","provider":"prospecbio","version":"1.0","type":"link"}