{"title":"Ankyrin Repeat Domain","description":"\u003ch2 class=\"highlited\"\u003e\u003cspan\u003eAbout ANKR \/ Ankyrin Repeat Domain:\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp\u003eANKR, or ankyrin repeat, is a collection of proteins that repeats in the genome. It consists of two alpha helices that are separated by loops similar to those in yeast Cdc10 and Drosophila Notch. Ankyrin repeat domains consist of ankyrin tandem repeats are the most common structural motifs in the body as well as in other living organisms. From the proteins of small bacterial, archaeal, and eukaryotic organisms to humans - they are prolific in the living world. They are most commonly seen in eukaryotes. Ankyrin repeat domains are common also in poxviruses, however they do not show up in most viruses.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eANKR Structure\u003c\/strong\u003e\u003cbr\u003eANKR usually shows up in repeats of four or six, and this is common in many proteins. However ankyrin itself, which is the namesake of this repeat structure, contains 24 repeats of this kind. The largest number of repeats that has been recorded is present in the organism giardia lamblia and consists of 34 repeats.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAnkyrin Repeat Domain Mechanism\u003c\/strong\u003e\u003cbr\u003eUsually when Ankyrin repeats are present inside the structure of a protein they will fold together and form a solenoid structure called ankyrin repeat domains. These domains are one of the most popular protein interaction platforms we see in nature. They occur in a wide array of proteins all over the living world including those of eukaryotes.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eANKR Interactions\u003c\/strong\u003e\u003cbr\u003eThe reason why there are few of these interactions present in viruses or prokaryotes is likely due to their horizontal gene transfers which differ from the vertical gene transfers seen in most reproductive systems.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAnkyrin Repeat Domain Function\u003c\/strong\u003e\u003cbr\u003eThe repeat has been found in proteins that have a lot of different functions such as cell cycle regulators, signal transductors, and even ion transporters. It is important to note that the ankyrin repeat domain is defined by its structure and not the function it performs in the body. The reason for this is that there is no specific function it seems to perform.\u003c\/p\u003e","products":[{"product_id":"ankra2-human","title":"ANKRA2 Human","description":"\u003cp\u003eAnkyrin Repeat Family A2 Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eAnkyrin Repeat, Family A (RFXANK-Like), 2, ANKRA,\nRFXANK-Like Protein 2, Ankyrin Repeat Family A Protein 2, ANKRA2.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"2µg","offer_id":43174149455956,"sku":"PRO-2062","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10µg","offer_id":43174149488724,"sku":"PRO-2062","price":145.0,"currency_code":"USD","in_stock":true},{"title":"100µg","offer_id":43174149521492,"sku":"PRO-2062","price":1200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-ankra2-human-PRO-2062.png?v=1776440546"},{"product_id":"ankrd1-human","title":"ANKRD1 Human","description":"\u003cp\u003eAnkyrin Repeat Domain 1 Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eAnkyrin Repeat Domain 1 (Cardiac Muscle), Cardiac Ankyrin Repeat Protein, Cytokine-Inducible Gene C-193 Protein, Ankyrin Repeat Domain-Containing Protein 1, Cytokine-Inducible Nuclear Protein, Liver Ankyrin Repeat Domain 1, BA320F15.2, CARP, ALRP, CVARP, MCARP, HA1A2, C193.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"2µg","offer_id":43174150504532,"sku":"PRO-1219","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10µg","offer_id":43174150537300,"sku":"PRO-1219","price":145.0,"currency_code":"USD","in_stock":true},{"title":"100µg","offer_id":43174150570068,"sku":"PRO-1219","price":1200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-ankrd1-human-PRO-1219.png?v=1776440550"},{"product_id":"ankrd54-human","title":"ANKRD54 Human","description":"\u003cp\u003eAnkyrin Repeat Domain 54 Protein Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eLIAR, Lyn-interacting ankyrin repeat protein.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"2µg","offer_id":43174151159892,"sku":"PRO-1480","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10µg","offer_id":43174151192660,"sku":"PRO-1480","price":145.0,"currency_code":"USD","in_stock":true},{"title":"100µg","offer_id":43174151225428,"sku":"PRO-1480","price":1200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-ankrd54-human-PRO-1480.png?v=1776440555"},{"product_id":"asb13-human","title":"ASB13 Human","description":"\u003cp\u003eAnkyrin Repeat And SOCS Box Containing 13 Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eAnkyrin repeat and SOCS box protein 13, ASB-13, ASB13, ankyrin repeat and SOCS box containing 13.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"5µg","offer_id":43174254510164,"sku":"PRO-2060","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20µg","offer_id":43174254542932,"sku":"PRO-2060","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":43174254575700,"sku":"PRO-2060","price":2700.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-asb13-human-PRO-2060.png?v=1776676975"},{"product_id":"asb8-human","title":"ASB8 Human","description":"\u003cp\u003eAnkyrin Repeat And SOCS Box Containing 8 Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eAnkyrin Repeat And SOCS Box Containing 8, ASB-8.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"2µg","offer_id":43174255296596,"sku":"PRO-1709","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10µg","offer_id":43174255329364,"sku":"PRO-1709","price":145.0,"currency_code":"USD","in_stock":true},{"title":"100µg","offer_id":43174255362132,"sku":"PRO-1709","price":1200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-asb8-human-PRO-1709.png?v=1776676978"}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/collections\/Image_698a4a4c-eea0-4b2a-93b5-f2d4e18502ca.png?v=1700646360","url":"https:\/\/prospecbio.com\/collections\/ankyrin-repeat-domain.oembed","provider":"prospecbio","version":"1.0","type":"link"}