- Name
- Description
- Cat#
- Pricings
- Quantity
Catalogue number
PRO-2814
Synonyms
Complement C3, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1, C3, CPAMD1.
Description
Rabbit Complement C3b is composed of 2 disulfide-linked chains having a molecular weight of 176kDa.
Source
Rabbit serum.
Physical Appearance
Sterile Filtered solution.
Formulation
C3b Rabbit solution contains 10mM sodium phosphate and 145mM NaCl, pH 7.2.
Stability
C3b is stable at 4°C if entire vial will be used within 2-4 weeks. Store, frozen below -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Purity
Greater than 85.0% as determined by SDS-PAGE.
Safety Data Sheet
Usage
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Background
Rabbit C3b serves as a critical opsonin, enhancing the recognition and engulfment of pathogens and immune complexes by phagocytic cells. Through its covalent attachment to target surfaces, C3b facilitates the recognition of foreign antigens and promotes their clearance by the immune system. C3b contributes to the inflammatory response by generating C5 convertase complexes, leading to the cleavage of C5 into C5a and C5b. C5a is a potent chemoattractant and activator of immune cells, promoting the recruitment of neutrophils and macrophages to sites of infection or tissue damage.